A man is dead after a crash on Interstate 80 on Wednesday night. Officials say it was around 11:20 p.m. when two vehicles collided on I-80 West, by Airport Road in Jefferson County. 

Officials say the vehicles collided when one of the drivers lost control and ended up crossing the median and driving the wrong way. 

A man from Ohio was pronounced dead. Two other people in the other vehicle were flown to UPMC Altoona for their injuries. 

Police have not released the name of the man who died, or the two people who were injured.